Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study

This study tracks tiny fragments of tumor DNA circulating in the blood (called circulating tumor DNA or ctDNA) in colorectal cancer patients to detect whether cancer has fully been removed after surgery or is likely to come back — before it shows up on a scan. **You may be eligible if...** - You are 18 years or older - You have a confirmed diagnosis of colorectal cancer (any stage) that may be treated with curative intent - You are willing to provide blood and tissue samples at various timepoints - If you had surgery (stages II–IV), you can enroll up to 3 months after the operation **You may NOT be eligible if...** - Your colorectal cancer is not being treated with intent to cure - You are unable or unwilling to provide samples or attend follow-up visits - You have another active cancer that would complicate results Talk to your doctor to see if this trial is right for you.