RecruitingPhase 2NCT04750616

NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial

NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury (NACAM) Trial

Sponsor

Kaiser Permanente

Enrollment

304 participants

Start Date

Sep 13, 2021

Study Type

INTERVENTIONAL

Conditions

Myocardial Injury Acute Kidney Injury Ischemia Reperfusion Injury

Summary

A Randomized, Double-blind, placebo-controlled Trial to Evaluate the Efficacy of Oral Nam for the Prevention of Acute Kidney Injury in Patients Undergoing On-Pump Cardiac Surgery

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Niacinamide and a drug called Placebo for people with acute kidney injury, ischemia reperfusion injury, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGNiacinamide

Niacinamide 3 grams on the day of surgery and post-surgical days one and two

DRUGPlacebo

Matched placebo on the day of surgery and post-surgical days one and two

Locations(1)

Kaiser Permanente San Francisco Medical Center

San Francisco, California, United States

View Full Details on ClinicalTrials.gov

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NCT04750616

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