RecruitingNCT04760977

Prehospital Management of Hypotensive Trauma in HEMS


Sponsor

Azienda Usl di Bologna

Enrollment

500 participants

Start Date

May 1, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

Up to today, inadequate evidences and knowledge exist about the best prehospital management of hypotensive trauma patients and its clinical consequence on the in-hospital recovery and mortality. Also new emerging therapies such as prehospital blood transfusion and REBOA (resuscitative endovascular balloon occlusion of the aorta) are lacking strong evidences in, eventually, reducing hospital mortality and improving outcomes. Moreover, prehospital emergency medicine is throughout Italy an heterogeneous system that has no unique standard operating procedures and, even among HEMS (helicopter emergency medical service), management and therapies on complex trauma patients may vary upon local policies. With this study we aim to enroll hypotensive trauma patients and study factors of prehospital rescue that can be associated with in-hospital mortality and recovery, eventually even with hospital outcome. For each patients data as demographic, kind of trauma (mechanism, injury scores), therapies and maneuvers will be recorded and then analyzed in comparison with in-hospital data such as need for transfusion, ABG parameters, length of stay (in-ward and ICU), need of therapies like invasive ventilation and renal replacement therapy, recovery and outcome


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Age > 18 years
  • Witnessed traumatic event managed by HEMS
  • Shock at first evaluation (Systolic blood pressure < 90 mmHg)
  • Suspect or obvious ongoing haemorrage

Exclusion Criteria1

  • Patients in cardiac arrest at HEMS arrival in which resuscitation is not started or interrupted by HEMS crew

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Interventions

DRUGDrugs administration

Antifibrinolytics, analgesics, sedatives, neuromuscular blocking agents

DEVICEResuscitative endovascular balloon occlusion of the aorta

Resuscitative technique for exsanguinating traumas

BIOLOGICALBlood transfusions

Transfuion of transported blood products for exsanguinating traumas

OTHERPrehospital management

Stay and play strategy vs scoop and run

DEVICEPrehospital eFAST

Prehospital thorax/abdomen extended focused assessment sonography for trauma


Locations(16)

Ospedale di Alessandria

Alessandria, Italy

Base HEMS Aosta

Aosta, Italy

Ospedale di Bolzano

Bologna, Italy

Base HEMS Borgo Sesia

Borgosesia, Italy

Base HEMS Cuneo-Levaldigi

Cuneo, Italy

Ospedale Careggi Firenze

Florence, Italy

Ospedale di Siena, Ospedale di Pisa

Grosseto, Italy

Ospedale di Siena, Ospedale di Pisa

Massa, Italy

Ospedale di Padova

Padova, Italy

Pavullo HEMS base

Pavullo nel Frignano, Italy

Pieve di Cadore HEMS base

Pieve di Cadore, Italy

Ospedale di Torino

Torino, Italy

Base HEMS Trento

Trento, Italy

Treviso hospital

Treviso, Italy

Udine FVG

Udine, Italy

Ospedale di Verona Borgo Trento

Verona, Italy

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NCT04760977


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