Critical Care Clinical Trials

19 recruiting

Critical Care Trials at a Glance

34 actively recruiting trials for critical care are listed on ClinicalTrialsFinder across 6 cities in 21 countries. The largest study group is Not Applicable with 16 trials, with the heaviest enrollment activity in Beijing, Vienna, and Amsterdam. Lead sponsors running critical care studies include Capital Medical University, Jian-Xin Zhou, and Bach Mai Hospital.

Browse critical care trials by phase

Treatments under study

About Critical Care Clinical Trials

Looking for clinical trials for Critical Care? There are currently 19 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Critical Care trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Critical Care clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 34 trials

Recruiting
Not Applicable

Effect of Semi-elemental Enteral Nutrition on Gastrointestinal Tolerance in Patients With Traumatic Brain Injury.

Traumatic Brain InjuryNeurocritical CareEnteral Feeding Intolerance
Tang-Du Hospital100 enrolled1 locationNCT07092423
Recruiting

Organ Dysfunction Score for Obstetric Patients

SepsisPregnancyPostpartum+2 more
Daniela Vasquez130 enrolled18 locationsNCT07068022
Recruiting
Phase 2

Fentanyl Versus Hydromorphone in Patients on Mechanical Ventilation

Mechanical VentilationSedation and AnalgesiaCritical Care, Intensive Care
Beth Israel Deaconess Medical Center300 enrolled1 locationNCT07224620
Recruiting

UP STUDY - Decipher Persistent Critical Illness Through in Deep Clinical Phenotyping.

Critical IllnessCritical CareCritical Care, Intensive Care+2 more
Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa7,000 enrolled7 locationsNCT07510776
Recruiting
Not Applicable

Behavioral Health Collaborative Care Model in Post-ICU Clinic Family Pilot

AnxietyDepression - Major Depressive DisorderPTSD+4 more
Medical University of South Carolina150 enrolled1 locationNCT07390786
Recruiting

Metabolomics Study on Postoperative Intensive Care Acquired Muscle Weakness

Muscle WeaknessMetabolomicsCritical Illness+4 more
Technical University of Munich20 enrolled3 locationsNCT03810768
Recruiting

Dosage of Early Rehabilitation of ICU Patients

PhysiotherapyCritical IllnessCritical Care, Intensive Care+2 more
Medical University of Vienna6,000 enrolled1 locationNCT06960642
Recruiting
Phase 4

CReep and Maintenance flUid Sodium Chloride ADministration rEduction in cRitically Ill adultS

Critical IllnessCritical Care, Intensive CareFluid and Electrolyte Imbalance+2 more
University Hospital, Antwerp640 enrolled4 locationsNCT07189091
Recruiting
Not Applicable

Inspiratory Effort-Targeted Pressure Support Ventilation (IT-PSV) Trial

Critical CareAcute Hypoxic Respiratory Failure
Capital Medical University619 enrolled1 locationNCT06526598
Recruiting

Timing and Dose of Fluid Deresuscitation in Critically Ill Patients

Fluid OverloadCritical Care, Intensive CareDeresuscitation
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)150 enrolled2 locationsNCT07275658
Recruiting
Not Applicable

Fluid Management and Individualized Resuscitation in Sepsis

SepsisShockEmergency Medicine+2 more
University Medical Center Groningen188 enrolled1 locationNCT07009665
Recruiting
Phase 2

A Clinical Trial of Interventions to Support Family Surrogates of Critically Ill Patients

TraumaCritical CareGrief+1 more
Weill Medical College of Cornell University172 enrolled3 locationsNCT05587517
Recruiting

Anesthesia and Critical Care Registry

AnesthesiaCritical Care
Università Vita-Salute San Raffaele30,000 enrolled1 locationNCT06033404
Recruiting

Pediatric Intensive Care Transport Registry

PediatricsCritical Care MedicineTransportation of Patients
Philipps University Marburg1,000 enrolled2 locationsNCT07070258
Recruiting
Not Applicable

The Role of Swan-Ganz Catheter in Hemodynamic Resuscitation for Patients With Cardiogenic Shock

EmergencyCardiogenic ShockHemodynamic Monitoring+6 more
Bach Mai Hospital108 enrolled1 locationNCT07062744
Recruiting
Not Applicable

Use of Nasal Pressure to Assess Inspiratory Effort Under Different Oxygen Treatments

Critical CareInspiratory Effort
Jian-Xin Zhou26 enrolled1 locationNCT06970990
Recruiting

Does Transcutaneous Phrenic Nerve Stimulation Prevent Diaphragm Atrophy?

Critical Care, Intensive Care
Bakirkoy Dr. Sadi Konuk Research and Training Hospital80 enrolled1 locationNCT06897774
Recruiting
Not Applicable

Comparison of Physiological Effects of Two High-Flow Tracheal Oxygen Versus T-Piece During Spontaneous Breathing Trials

Critical Care
Jian-Xin Zhou20 enrolled1 locationNCT06816706
Recruiting

Effect of Reduced Vasopressors on Mortality in ECMO-supported Cardiogenic Shock Patients

Heart FailureCardiogenic ShockExtracorporeal Membrane Oxygenation+3 more
Xiaotong Hou534 enrolled1 locationNCT06862700
Recruiting
Not Applicable

Safety and Efficacy of Enhanced Recovery After Surgery in Neurocritical Care

Traumatic Brain InjuryNeurocritical CareCerebrovascular Disease+1 more
Shanghai 6th People's Hospital80 enrolled1 locationNCT06241482