CMR Versus CT in Coronary Artery Disease
Comparison of Cardiovascular Magnetic Resonance and Computed Tomography With Fractional Flow Reserve in the Diagnosis of Suspected Coronary Artery Disease
University of Leicester
300 participants
Nov 5, 2020
OBSERVATIONAL
Conditions
Summary
CONCORD is a prospective observational study evaluating the diagnostic accuracy of cardiovascular magnetic resonance (CMR) and computed tomography with fractional flow reserve (CT-FFR) in patients with suspected coronary artery disease, using invasive fractional flow reserve (FFR) as the reference standard.
Eligibility
Inclusion Criteria2
- Patients aged ≥18 years
- Referred for invasive coronary angiography for investigation of chest pain
Exclusion Criteria11
- Recent acute coronary syndrome (< 6 months)
- Previous coronary artery bypass grafting
- Severe claustrophobia
- Absolute contraindications to CMR - those with MR conditional or safe devices will be included
- Second-/third-degree atrioventricular block
- Severe chronic obstructive pulmonary disease
- Moderate-severe asthma
- Estimated glomerular filtration rate <30 ml/min/1.73m2
- Women who are pregnant, breast-feeding or of child-bearing potential( premenopausal women)
- Contraindication to iodinated contrast
- Participation in a research study involving an investigational product in the past 12 weeks
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Interventions
multi-parametric CMR assessment and CT coronary angiography with FFR assessment
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04761991