A Prospective, Phase II Trial Using ctDNA to Initiate Post-operation Boost Therapy After Adjuvant Chemotherapy in TNBC

This study is for people with triple-negative breast cancer (a type that lacks the three most common receptors, making it harder to treat) who have finished surgery and chemotherapy but still show signs of cancer in a blood test. It tests whether giving additional treatment guided by that blood test (ctDNA — tiny fragments of cancer DNA in blood) can reduce the chance of the cancer coming back. **You may be eligible if...** - You are 18 or older - You have Stage II or III triple-negative breast cancer - You have had surgery and chemotherapy - After treatment, a blood test (ctDNA) is still positive, suggesting cancer may still be present **You may NOT be eligible if...** - Your ctDNA test is negative after treatment - You have not completed the standard surgery and chemotherapy - You have other active cancers Talk to your doctor to see if this trial is right for you.