RecruitingNot ApplicableNCT04817566

Cognitive Training and Brain Stimulation in Women With Post-chemotherapy Cognitive Impairment

Neuromodulation Through Brain Stimulation-assisted Cognitive Training in Patients With Post-chemotherapy Cognitive Impairment


Sponsor

University Medicine Greifswald

Enrollment

52 participants

Start Date

Nov 2, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of this study is to investigate whether a high definition tDCS-accompanied intensive cognitive training of working memory leads to performance improvement in women with post-chemotherapy cognitive impairment after breast cancer treatment.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying whether combining computerized brain training exercises with a mild form of noninvasive brain stimulation (called tDCS, which sends a tiny electrical current through the scalp) can help women who experience memory and thinking problems after breast cancer chemotherapy — commonly called "chemo brain." **You may be eligible if...** - You received chemotherapy for breast cancer at least 6 months ago - You have noticed problems with your memory or concentration since treatment - You are between 18 and 65 years old - You are right-handed **You may NOT be eligible if...** - You had dementia before your cancer treatment - You have epilepsy or a history of seizures - You have a moderate-to-severe psychiatric disorder or substance use problem - You have a reason you cannot receive brain stimulation (e.g., metal implants in or near the head) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEAnodal tDCS

Anodal transcranial direct current stimulation (tDCS), 9 sessions with 20 minutes stimulation each (2 mA).

DEVICESham tDCS

Sham transcranial direct current stimulation (tDCS), 9 sessions with 30 sec stimulation each (2 mA) to ensure blinding of participants.

BEHAVIORALIntensive cognitive training

Intensive cognitive training of a letter memory updating task, 9 sessions for approximately 20 min


Locations(1)

University Medicine Greifswald

Greifswald, Germany

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NCT04817566


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