Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)
Sympathetic Neural Patterns and Transduction in Obesity-associated Hypertension
University of Texas Southwestern Medical Center
100 participants
Jul 18, 2021
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to understand how the nervous system communicates to blood vessels to increase blood pressure during stress. The study will also investigate how hypertension and obesity influence the nervous system and vascular function. The study will involve measuring sympathetic nervous system activity and blood flow during common laboratory physiological stress protocols (e.g. hypoxia, exercise), and in response to infusion of drugs that cause vasodilation or vasoconstriction.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
intra-arterial infusion of neuropeptide Y
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04838678