RecruitingNCT04845893

Observational Study on Skeletal Ewing's Sarcoma

Observational Study on Treatment of Skeletal Ewing Sarcoma at Diagnosis


Sponsor

Italian Sarcoma Group

Enrollment

100 participants

Start Date

Jun 1, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

Observational prospective trial aimed to collect the collect demographic, clinical, surgical, pathological and molecular characteristics and treatment from patients affected by skeletal Ewing Sarcoma


Eligibility

Min Age: 0 YearsMax Age: 49 Years

Inclusion Criteria6

  • Diagnosis of Ewing's sarcoma of the bone
  • Diagnosis of Ewing-like sarcoma (round cell sarcoma with fusion of the EWSR1 gene with others not of the ETS family, sarcoma with CIC rearrangement or sarcoma with BCOR rearrangement)
  • Diagnosis of extraosseous Ewing's sarcoma for patients
  • Age at diagnosis \<50 years
  • Assessment of the extent of the disease at onset in accordance with the European Society of Medical Oncology guidelines
  • Patients or parents oe guardians of minors who have given their written informed consent to participate in the study

Exclusion Criteria1

  • \. Presence of comorbid factors who can compromise the compliance of the treatment plan or the evaluation of the outcomes, including but not limited to organ pathologies that contraindicate the use of chemotherapy and psychological or social conditions that do not allow for adequate compliance treatment or adequate follow-up

Interventions

OTHERTreatment of Ewings Sarcoma of bone according clinical practice (includes drugs, surgery, radiotherapy or any other received treatments)

This observational study collects all the treatments received by the patients according clinical practices or experimental trials and therefore includes drug/biological/surgical/ radiotherapy and any other applicable treatments


Locations(19)

Istituto Clinico Humanitas

Rozzano, MI, Italy

Centro di Riferimento Oncologico - Unit of Medical Oncology

Aviano, Pordenone, Italy

I.R.C.C. - Unit of Medical Oncology

Candiolo, Torino, Italy

Azienda ospedaliero universitaria consorziale policlinico - bari

Bari, Italy

A.O. Universitaria Policlinico S. Orsola Malpighi di Bologna

Bologna, Italy

Istituto ortopedico Rizzoli

Bologna, Italy

A.O. Universitaria Meyer

Florence, Italy

Istituto Giannina Gaslini

Genova, Italy

FONDAZIONE IRCCS Istituto Nazionale dei Tumori

Milan, Italy

FONDAZIONE IRCCS Istituto Nazionale dei Tumori

Milan, Italy

Azienda Ospedaliera Santobono Pausilipon

Napoli, Italy

Azienda Ospedaliera di Padova

Padua, Italy

ARNAS P. O. "Civico e Benfratelli"

Palermo, Italy

Azienda Ospedaliera Universitaria di Parma

Parma, Italy

Azienda Ospedaliero-Universitaria Pisana

Pisa, Italy

Ospedale Pediatrico Bambin Gesu'

Roma, Italy

Istituto Regina Elena - IFO

Rome, Italy

Ospedale Infantile Regina Margherita - Unit of Paediatric Oncoematology

Torino, Italy

IRCCS materno infantile Burlo Garofolo

Trieste, Italy

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NCT04845893


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