Analysis of the Evolution of SUVmax by Quantitative Analysis Method of Bisphosphonate Scintigraphy
Analysis of the Evolution of SUVmax by Quantitative Analysis Method of Bisphosphonate Scintigraphy for the Follow-up of Patients With Transthyretin Amyloidosis Treated With Tafamidis
GCS Ramsay Santé pour l'Enseignement et la Recherche
30 participants
Feb 25, 2021
INTERVENTIONAL
Conditions
Summary
Recently, treatment with tafamidis in patients with cardiac ATTR lead to a significant reduction in mortality. The Perugini score is commonly used on planar bone scans to differentiate cardiac ATTR from other amyloidosis or normal patients but fails to evaluate amyloid burden and patient prognosis. Although semi-quantitative methods have been suggested to evaluate the amyloid burden, there a need for quantitative methods for longitudinal assessment of the disease.
Eligibility
Plain Language Summary
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Interventions
Bone scintigraphy
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04849754