Cardiac Amyloidosis Clinical Trials

26 recruiting

Cardiac Amyloidosis Trials at a Glance

31 actively recruiting trials for cardiac amyloidosis are listed on ClinicalTrialsFinder across 6 cities in 16 countries. The largest study group is Not Applicable with 6 trials, with the heaviest enrollment activity in Boston, London, and Hefei. Lead sponsors running cardiac amyloidosis studies include Life Molecular Imaging GmbH, Brigham and Women's Hospital, and Tianjin Medical University.

Browse cardiac amyloidosis trials by phase

Treatments under study

About Cardiac Amyloidosis Clinical Trials

Looking for clinical trials for Cardiac Amyloidosis? There are currently 26 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cardiac Amyloidosis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cardiac Amyloidosis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 31 trials

Recruiting
Phase 3

[64Cu]FBP8 PET for Early Detection of Intracardiac Thrombus in Amyloid Cardiomyopathy

Cardiac Amyloidosis
Brigham and Women's Hospital20 enrolled1 locationNCT07560306
Recruiting

A Study Of Deep Learning For Echo Analysis, Tracking, And Evaluation

CardiomyopathyCardiac AmyloidosisIschemic Heart Disease
Mayo Clinic10,040,000 enrolled1 locationNCT07308704
Recruiting

Cardiac Amyloidosis pRevaleNce of in OLDer Subjects Affected by Heart Failure

Cardiac Amyloidosis
Gérond'if637 enrolled36 locationsNCT06427304
Recruiting
Phase 1

Test-retest Study With [18F]FBB in Cardiac Amyloidosis

Cardiac Amyloidosis
Life Molecular Imaging GmbH15 enrolled2 locationsNCT06790394
Recruiting

Multicenter Study for the Validation of an AI-based ECG Platform for Early Cardiac Amyloidosis Diagnosis

Transthyretin Cardiac Amyloidosis
Idoven 1903 S.L.2,000 enrolled10 locationsNCT06978660
Recruiting
Not Applicable

CHEST-CA: Study of Chest Pain and Hidden Cardiac Amyloidosis

Chest PainCardiac Amyloidosis
Rigshospitalet, Denmark300 enrolled1 locationNCT07435168
Recruiting

Precision Diagnosis and Risk Stratification of Rare Cardiomyopathies Based on Novel Cardiac Magnetic Resonance Techniques

Noonan SyndromeFabry DiseaseCardiac Amyloidosis+4 more
Chinese Academy of Medical Sciences, Fuwai Hospital1,000 enrolled1 locationNCT07336394
Recruiting
Not Applicable

Amylo-Shiatsu-Acute-Chronic: Effects of Shiatsu on Symptoms and Quality of Life of Amyloidosis Patients

Cardiac Amyloidosis
Assistance Publique - Hôpitaux de Paris108 enrolled1 locationNCT06197165
Recruiting
Phase 4

Real-Life Clinical Efficacy of Acoramidis in Participants With ATTR-CM and Association With Cardiac Biomarkers

Transthyretin-type Cardiac Amyloidosis
Alexion Pharmaceuticals, Inc.200 enrolled16 locationsNCT07306949
Recruiting
Phase 3

Efficacy of [18F]Florbetaben PET for Diagnosis of Cardiac AL Amyloidosis

AL AmyloidosisCardiac AmyloidosisATTR Amyloidosis
Life Molecular Imaging GmbH200 enrolled14 locationsNCT05184088
Recruiting

[18F]FT8 PET Imaging in Immunoglobulin Light Chain Amyloidosis

AmyloidosisCardiac AmyloidosisHealthy Subjects+1 more
Tianjin Medical University25 enrolled2 locationsNCT07232459
Recruiting

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

Cardiac AmyloidosisCardiomyopathy, HypertrophicLumbar Spinal Stenosis+3 more
Columbia University1,663 enrolled6 locationsNCT06034405
Recruiting

US Benchmarking Clinical Study

Cardiac AmyloidosisHFpEF - Heart Failure With Preserved Ejection FractionHFmrEF+2 more
eMyosound SAS150 enrolled3 locationsNCT07215715
Recruiting
Not Applicable

PATHWAY-RCT: Preventing Admission To Hospital With Attr cardiomyopathY

Cardiac Amyloidosis
Richmond Research Institute320 enrolled1 locationNCT05098665
Recruiting
Phase 4

Safety, Efficacy, and Pharmacokinetics of Tafamidis in Patients With Transthyretin-mediated Amyloidosis Post Orthotopic Heart Transplantation

Transthyretin Cardiac Amyloidosis
University of Texas Southwestern Medical Center25 enrolled4 locationsNCT05489523
Recruiting

Hybrid Florbetaben PET/MRI for Imaging of Cardiac Amyloidosis

Cardiac Amyloidosis
University Hospital, Essen25 enrolled1 locationNCT07154381
Recruiting

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Transthyretin-Related (ATTR) Familial Amyloid CardiomyopathyTransthyretin-Related (ATTR) Familial Amyloid PolyneuropathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics72 enrolled4 locationsNCT05697861
Recruiting

Pan-Amyloid PET/CT in Various Amyloid-Related Disease

AmyloidosisCardiac AmyloidosisAmyloid
Tianjin Medical University500 enrolled2 locationsNCT07130565
Recruiting
Not Applicable

CAPACITY (Cardiac Amyloidosis and Physical ACtivITY) Study

Cardiac Amyloidosis
Wake Forest University Health Sciences50 enrolled1 locationNCT06096675
Recruiting

Artificial Intelligence Guided Echocardiographic Screening of Rare Diseases (EchoNet-Screening)

Cardiac Amyloidosis
Cedars-Sinai Medical Center300 enrolled1 locationNCT05139797