RecruitingNCT04853186

Impact Study of Cholera Vaccination in Endemic Areas - Clinical Surveillance

Cholera Control in Endemic Regions of Africa: Clinical Surveillance and Cholera Shedding Study in the Context of Mass Vaccination Campaigns, Democratic Republic of the Congo

Sponsor

Epicentre

Enrollment

6,000 participants

Start Date

May 11, 2021

Study Type

OBSERVATIONAL

Conditions

Cholera

Summary

This project aims to fill this essential knowledge gap by assessing the impact of oral cholera vaccine mass campaigns in 2 sites (urban and rural) in DRC, described in this protocol. The evidence generated from this project will be key to develop future strategies regarding cholera vaccine use in endemic settings, including places with higher burden in terms of cholera mortality.

Eligibility

Inclusion Criteria3

For Surveillance in study CTCs
All patients presenting at the time of the study to any selected Cholera Treatment Center/Cholera Treatment Unit (CTC/CTU), matching the case definition and giving his/her consent (or assent for children 8 to 17 years old) to participate in the study will be eligible.
present to any selected CTC/CTU, match the case definition, participate to the clinical surveillance activity and test positive to RDT OR

Exclusion Criteria3

Patients who decline to participate will be excluded from the study.
Follow up of individuals with active cholera shedding:
\- Individuals who decline to participate will be excluded from the study, as well as households for whom the head of the household (and his or her representative) decline the participation of his/her household.

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