RecruitingNCT04885244

Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery

Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery (MIS)


Sponsor

International Spine Study Group Foundation

Enrollment

500 participants

Start Date

Jul 28, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients treated with minimally invasive approach, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.


Eligibility

Min Age: 18 Years

Inclusion Criteria17

  • \>18 years of age at the time of treatment
  • Diagnosis of adult congenital, degenerative, idiopathic, neuromuscular, inflammatory or iatrogenic spinal deformity
  • EOS full body or standing 36" AP \& Lateral images of entire spine
  • Surgery to be schedule to take place within 6 months (otherwise PROMs/Radiographic images to be recollected)
  • AND Either:
  • One of the following Radiographic criteria:
  • PI-LL ≥ 25 degrees
  • Thoracolumbar/lumbar scoliosis ≥ 20 degrees
  • SVA \>10cm
  • PT \> 30 OR
  • One of the Following Procedural criteria:
  • Surgery to include \> 3 levels percutaneous posterior spinal instrumentation or 3 level stand-alone interbody. (Levels = vertebra (i.e. percutaneous screws at L2, L3, L4 would be eligible for posterior instrumentation and/or L3-L4, L4-L5 would be eligible as stand-alone for interbodies)
  • Posterior UIV and LIV must be placed percutaneously
  • Single-position surgery ≥ 3 levels fused (Levels=vertebra; S1 is counted as a level; S2 \&/or pelvis/ilium is not)
  • Staged ≥ 3 levels fused with percutaneous pedicle screws
  • column osteotomy with percutaneous fixation
  • ACR incorporating open or percutaneous fixation as long as UIV and LIV are percutaneous screws

Exclusion Criteria6

  • Deformity due to acute trauma
  • Active spine tumor or infection
  • Patient is unwilling or unable to complete questionnaires
  • Women who are pregnant
  • Prisoners
  • Open Posterior spinal fusion is planned (Open Anterior, i.e. ALIF, is acceptable)

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Interventions

PROCEDUREIndex or spine revision surgery for complex adult spinal deformity

Surgical interventions will be patient specified by treating surgeon.


Locations(12)

Barrow Neurological Institute

Phoenix, Arizona, United States

Shiley Center for Orthopaedic Research and Education at Scripps Clinic

La Jolla, California, United States

Cedars-Sinai Medical Center

Los Angeles, California, United States

University of California - San Francisco Medical Center

San Francisco, California, United States

University of Miami

Miami, Florida, United States

Rush University, Department of Neurosurgery

Chicago, Illinois, United States

Louisiana Spine Institute

Shreveport, Louisiana, United States

University of Michigan, Department of Neurosurgery

Ann Arbor, Michigan, United States

Columbia University - New York-Presbyterian Och Spine Hospital

New York, New York, United States

Duke University Health System

Durham, North Carolina, United States

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States

Semmes-Murphey

Memphis, Tennessee, United States

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NCT04885244


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