RecruitingNCT04906863

Genetic Studies of Early-onset Dementia

Sponsor

Columbia University

Enrollment

1,000 participants

Start Date

Sep 14, 2016

Study Type

OBSERVATIONAL

Conditions

Dementia, Early Onset

Summary

The aim of this study is to identify genetic factors that contribute to risk and progression of early-onset dementia (loss of memory function before the age of 70 years) across all ethnic groups, including Alzheimer's Disease, mild cognitive impairment and other dementias.

Eligibility

Min Age: 18 Years

Inclusion Criteria2

years and older
Individuals diagnosed with dementia, their family members and unrelated healthy controls without dementia.

Exclusion Criteria1

Individuals with competing diagnosis such as Huntington's disease, traumatic brain injury, drug or alcohol abuse, or schizophrenia, etc., unless family members of a dementia affected individual

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Interventions

GENETICBlood draw

Blood draw for identification of genetic variants associated with the development of memory problems

OTHERNeurocognitive testing

Brief memory test

OTHERMedical questionnaire

Collection of medical history

Locations(1)

Columbia University Irving Medical Center

New York, New York, United States

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NCT04906863