Early Tranexamic Acid and Modulating the Inflammatory Response in Sepsis
Could Early Tranexamic Acid Safely Serve as an Anti-inflammatory Treatment for Patients With Sepsis? A Randomized Double Blind Controlled Trial
Assiut University
80 participants
Jun 5, 2021
INTERVENTIONAL
Conditions
Summary
In this study, our aim is to investigate the role tranexamic acid in modulating inflammation in patients with sepsis.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
administer 1 gram of TXA in 100 ml of 0.9% normal saline, intravenous over 10 minutes as soon as possible but no later than three hours after diagnosis, infuse a second gram of TXA IV over 8 hours in 0.9% normal saline for first 3 days.
administer the same volume (100ml normal saline) and same duration (first three days).
Locations(1)
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NCT04910464