Inspiratory Muscle Strength Training in Chronic Kidney Disease

This study tests whether inspiratory muscle strength training (a breathing exercise using a resistance device) can lower blood pressure and improve kidney and cardiovascular health in older adults with both chronic kidney disease and poorly controlled high blood pressure. **You may be eligible if...** - You are 50 years or older (women must be post-menopausal) - You have chronic kidney disease stage 3 or 4 (moderate to severe kidney impairment) - You have a history of inadequately controlled blood pressure (systolic 120–159 mmHg) and have been on a stable blood pressure medication regimen for at least 6 weeks - Your weight has been stable for the past 3 months **You may NOT be eligible if...** - You require dialysis - You have significant lung disease (COPD, interstitial lung disease, cystic fibrosis, or uncontrolled asthma) - You have had a spontaneous collapsed lung, burst eardrum, or recent chest surgery that has not fully healed - You plan to start weight-loss medications during the study Talk to your doctor to see if this trial is right for you.