RecruitingPhase 2Phase 3NCT04932577

Faecal Microbiota Transplantation for Liver Cirrhosis

Faecal Microbiota Transplantation to Prevent Complications, Progression and Mortality of Liver Cirrhosis


Sponsor

University of Aarhus

Enrollment

220 participants

Start Date

Jul 1, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose is to investigate the effect of faecal microbiota transplantation (FMT) on complications, progression, and mortality of patients with liver cirrhosis. Further, the investigators want to examine the impact of FMT on the gut microbiota, gut barrier function, systemic inflammation, and immune function.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called Faecal microbiota transplantation and a biological treatment called Placebo for people with liver cirrhosis. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALFaecal microbiota transplantation

All participant will receive three applications of either FMT or placebo and afterwards followed for 1 year.

BIOLOGICALPlacebo

Placebo


Locations(1)

Department of Hepatology and Gastroenterology, Aarhus University Hospital

Aarhus, Denmark

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NCT04932577


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