Comparison of Segmentectomy Versus Lobectomy for Non-small Cell Lung Cancer ≤ 2 cm in the Middle Third of the Lung Field

This study compares two lung cancer surgery approaches — segmentectomy (removing just the tumor-containing lung segment) versus lobectomy (removing the whole lobe) — for small non-small cell lung cancers (6–20 mm) located in the middle zone of the lung. **You may be eligible if...** - You are between 18 and 75 years old - Your lung tumor is between 6 mm and 20 mm in size, located in the middle third of the lung - Your cancer is confined to the lung (no lymph node or distant spread) - Your lung function is adequate to tolerate either type of surgery (FEV1 ≥1L and ≥70%) - The tumor is a single nodule (or any additional nodule is very small) - You are in good enough health for surgery (ECOG 0-2) **You may NOT be eligible if...** - Your tumor is in the right middle lobe - You have had another cancer in the last 5 years - You have received prior treatment (chemotherapy or radiation) for this tumor - Your lung function is insufficient for surgery Talk to your doctor to see if this trial is right for you.