RecruitingPhase 4NCT04957329
Effect of Benzalkonium Chloride Preserved and Preservative-free Latanoprost Eye Drops on Conjunctival Goblet Cells
Department of Ophthalmology, Rigshospitalet-Glostrup Valdemar Hansens Vej 13, 2600 Glostrup, Denmark
Sponsor
Rigshospitalet, Denmark
Enrollment
28 participants
Start Date
Sep 1, 2021
Study Type
INTERVENTIONAL
Conditions
Summary
a randomized, investigator-blind, interventinal study will compare the effect of benzalkonium-chloride (BAK) preserved and preservative-free (PF) eye drops on conjunctival goblet cells.
Eligibility
Min Age: 18 Years
Inclusion Criteria4
- Age \>18years
- Danish speaking
- Open angle glaucoma or ocular hypertension
- Average intraocular pressure equal to or above 22 mmHg
Exclusion Criteria1
- a. history of significant eye diseae (including okular trauma) other than open angle glaucoma and ocular hypertension d. treatment with steroids within the last 3 months from inclusion e. Significant untreated systemic disease such as hypertension, heart failure, diabetes mellitus, stroke, lung disease and autoimmune diseases. Diseases are not reason for exclusion if they are well treated or does not need treatment g. pregnant or breast feeding h. women using unsafe anticonception i. allergy towards trial medication j. patients who cannot cooperate in eye examination k. ocular surface defects l. need for polytherapy in glaucoma treatment
Interventions
DRUGXalatan
Eye drop
DRUGMonoprost
Eye drop
Locations(2)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04957329
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