RecruitingPhase 1NCT04975152

Neoadjuvant Cemiplimab in Newly Diagnosed or Recurrent Stage I-II Merkel Cell Carcinoma and Locoregionally Advanced Cutaneous Squamous Cell Carcinoma

Neoadjuvant Cemiplimab in Newly Diagnosed or Recurrent Stage I-II Merkel Cell Carcinoma and Locoregionally Advanced Cutaneous Squamous Cell Carcinoma: Safety and Biomarker Analysis


Sponsor

H. Lee Moffitt Cancer Center and Research Institute

Enrollment

36 participants

Start Date

Oct 22, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical research study is to determine if Cemiplimab-rwlc (called Cemiplimab in this document) given prior to tumor resection surgery is safe and effective in treating (1) Merkel Cell Carcinoma or (2) Cutaneous Squamous Cell Carcinoma (CSCC).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Cemiplimab-Rwlc for people with cutaneous squamous cell carcinoma and merkel cell carcinoma. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGCemiplimab-Rwlc

Flat dose of cemiplimab-rwlc 350 mg IV every 3 weeks, up to 9 cycles.


Locations(1)

Moffitt Cancer Center

Tampa, Florida, United States

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NCT04975152


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