RecruitingNot ApplicableNCT04990713

QoR40 Between Intercostal Block and Intercostal Block and Serratus Plane Catheter During VATS

QORVATS Study. A Randomized Controlled, Triple Blinded to Compare the Quality of Recovery (QoR 40) Between Intercostal Block and a Combination of Intercostal Nerve Block With Serratus Plane Catheter for Patient's Undergoing VATS Procedures.


Sponsor

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Enrollment

200 participants

Start Date

Jun 30, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Video assisted thoracic surgery (VATS) has emerged as standard of care for majority of thoracic surgeries. It is less invasive compared to thoracotomy and is associated with improved perioperative outcomes \[1-3\]. Good perioperative analgesia after thoracic surgery will enable pulmonary toilet, early chest physiotherapy and mobilisation, \[4,5,6\]. Thirty-day hospital visits and hospital readmissions at London Health Sciences Centre (LHSC) is around 21% and 9% respectively \[7\]. One of the top five determinant for hospital visit and readmission in 30 days, was persistent post operative pain \[7\]. Several options to analgesia are available for patients undergoing VATS procedure. Systemic opioid based multimodal analgesia, central neuraxial blocks like thoracic epidural and peripheral nerve blocks are different available options, and their practise varies across institution \[4,8,9\]. Thoracic epidural or paravertebral blocks can be challenging to perform with high failure rates \[10-12\]. Fascial plane blocks (SAB; ESP) are in vogue in the present era \[13-16\]. They are easy to perform and do not require similar dexterity as needed to perform thoracic epidural or paravertebral blocks. They have minimal side effects and provide the options for continuous infusion for prolonged analgesia. They have become an effective part of multimodal analgesia and have established their roles in ERAS (enhanced recovery after surgery) protocol for VATS procedures. SAB has become a common practise at our institution with proved clinical efficacy. Perioperative Surgical Home is a patient centric team-based approach to improve patient's experiences in the perioperative period and thus improve healthcare \[17\]. Quality of Recovery (QoR) is a key determinant to perioperative surgical home and can be measured using the QoR 40 score \[18\]. This is a well validated score with a minimal important clinical difference (MICD) of 6.3 \[19\]. Quality of recovery combines five dimensions of health: patient support, comfort, emotions, physical independence and pain to achieve a single patient outcome - improved patient care \[18\]. The investigators hypothesize the that patients undergoing VATS lung resections using a combination of intercostal nerve block plus continuous SAB catheter infusion of local anesthetics will have a 20% increase in their QoR-40 score 24hour after the surgery compared to a single shot intercostal nerve block.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two pain management approaches for patients having lung surgery (VATS — video-assisted thoracic surgery): intercostal nerve block alone versus intercostal nerve block plus a continuous pain-blocking catheter placed near the chest wall (serratus plane block). Researchers want to find out which method helps patients recover better after surgery. You may be eligible if: - You are 18 years of age or older - You are scheduled for elective lung surgery (wedge resection, segmentectomy, bi-lobectomy, or lobectomy) via VATS - Your health status is rated ASA 1-4 You may NOT be eligible if: - You have refused to participate - This is emergency surgery - You have allergies to local anesthetics - Your BMI is over 40 - You have an active chest wall or systemic infection - You have had a previous lung resection on the same side - You have had chronic pain (lasting more than 6 months) - Your surgery converts to open (thoracotomy) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURESerratus Plane Block (Local Anesthetic) and Intercostal Block (Local Anesthetic)

Patients will receive local anesthetic via serratus plane block as opposed to saline placebo

PROCEDURESerratus Plane Block (Placebo) and Intercostal Block (Local Anesthestic)

Patients will receive saline placebo via serratus plane block


Locations(1)

London Health Sciences Centre

London, Ontairo, Canada

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NCT04990713


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