RecruitingNCT05027685

The "Global Paradise System" Registry

The "Global Paradise® System" Registry


Sponsor

ReCor Medical, Inc.

Enrollment

3,000 participants

Start Date

Jan 13, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The GPS Registry is a multi-centre, single-arm, non-interventional (observational) registry. In addition to collecting data from patients treated as per standard clinical practice, the Registry will also regularly collect telemetric Home Blood Pressure (HBP) measurements and Patient Reported Outcome (PRO) data via a standardized quality of life questionnaire. The objective of the GPS Registry is to document the long-term safety and effectiveness of the commercially available Paradise Ultrasound Renal Denervation System when used per its labelling in patients deemed to be candidates for RDN as per physician's assessment.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Appropriately signed and dated informed consent
  • Age ≥18 at time of consent
  • Patient candidate for renal denervation with the Paradise System based on physician's assessment OR Patient treated with the Paradise Ultrasound Renal Denervation System within the 6 months prior to consent

Exclusion Criteria11

  • Patients who meet any of the contraindications listed in the Instructions for Use will be excluded.
  • The contraindications are:
  • Stented renal artery
  • Less than 18 years of age
  • Pregnant
  • Known allergy to contrast medium
  • Renal arteries diameter \< 3 mm and \> 8 mm
  • Renal artery with Fibromuscular (FMD) disease
  • Renal artery aneurysm
  • Renal artery stenosis of any origin \>30%
  • Iliac/femoral artery stenosis precluding insertion of the Paradise catheter

Interventions

DEVICEThe Paradise Ultrasound Renal Denervation System

The CE-marked and commercially available ReCor Medical Paradise Ultrasound Renal Denervation System (Paradise System) is a catheter-based device designed to use ultrasound energy to thermally ablate the nerves surrounding the renal artery and serving the kidney.


Locations(35)

OLV Ziekenhuis Aalst

Aalst, Belgium

CHU Saint Pierre Brussels

Brussels, Belgium

UCL St Luc

Brussels, Belgium

CHU Bordeaux Hôpital St. André

Bordeaux, France

HEGP (Hôpital Européen Georges Pompidouv) Paris

Paris, France

Centre Hospitalier de Pau

Pau, France

Universitäts-Herzzentrum Freiburg Bad Krozingen

Bad Krozingen, Germany

Charité Universitätsmedizin Berlin Campus Benjamin Franklin

Berlin, Germany

Klinikum Coburg GmbH

Coburg, Germany

Universitätsklinikum Köln

Cologne, Germany

Klinikum Lippe GmbH Detmold

Detmold, Germany

Herzzentrum Dresden GmbH Universitätsklinik

Dresden, Germany

Universitätsklinikum Düsseldorf

Düsseldorf, Germany

Universitätsklinikum Erlangen

Erlangen, Germany

Cardiovasculäres Centrum (CVC) Frankfurt

Frankfurt, Germany

St. Barbara-Klinik Hamm Heessen

Hamm, Germany

University Clinic of Saarland - Homburg

Homburg, Germany

Herzzentrum Leipzig GmbH

Leipzig, Germany

Sana Kliniken Lübeck gGmbH

Lübeck, Germany

Marienhaus Klinikum Mainz

Mainz, Germany

Detusches Herzzentrum München (DHM)

München, Germany

Robert-Bosch-Krankenhaus GmbH Stuttgart

Stuttgart, Germany

Schwarzwald-Baar Klinikum Villingen-Schwenningen

Villingen-Schwenningen, Germany

Centre Hospitalier Princesse Grace Monaco

Monaco, Monaco

Noordwest Ziekenhuisgroep

Alkmaar, Netherlands

Erasmus MC Rotterdam

Rotterdam, Netherlands

HUG Geneve Switzerland

Geneva, Switzerland

Heart Center Lucerne -Luzerner Kantonsspital

Lucerne, Switzerland

Royal Bournemouth Hospital, Bournemoth

Bournemouth, United Kingdom

Kent and Canterbury Hospital, Canterbury

Canterbury, United Kingdom

University Hospital Wales, Cardiff

Cardiff, United Kingdom

Queen Elizabeth Hospital, Glasgow

Glasgow, United Kingdom

Hammersmith Hospital (Imperial College Healthcare NHS Trust)

London, United Kingdom

WHRC - Barts Health, London

London, United Kingdom

Freeman Hospital, Newcastle

Newcastle, United Kingdom

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05027685


Related Trials