RAPid SimPLE Targeted Radiation Treatment for Brain Metastases

This study tests a simplified, fast approach to targeted radiation therapy for brain metastases — cancer that has spread to the brain. Rather than complex planning, this approach aims to start treatment faster while still accurately targeting each tumor spot. **You may be eligible if...** - You are 18 or older with cancer that has spread to the brain - Your cancer did not originate in the blood or immune system - You have brain metastases that can be mapped and targeted with radiation - You also have cancer elsewhere in the body - You can complete quality-of-life questionnaires and attend regular imaging check-ups - You are in reasonable physical condition (Karnofsky score ≥50) **You may NOT be eligible if...** - Your brain condition requires urgent treatment (e.g., imminent brain herniation) - Your cancer prognosis score suggests very poor expected survival - You have leptomeningeal disease (cancer spreading along the brain lining) Talk to your doctor to see if this trial is right for you.