RecruitingNCT05056818

Comparison of Synthetic Mammography Versus Full-Field Digital Mammography in Image Interpretation and Performance Metrics


Sponsor

M.D. Anderson Cancer Center

Enrollment

750 participants

Start Date

Dec 15, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

This study compares synthetic mammography to full-field digital mammography in image interpretation and performance metrics. Digital breast tomosynthesis (DBT) has previously been found to be superior in performance to standard digital mammography in both screening and diagnostic settings for the early detection and improved diagnosis of breast cancers. DBT in combination with full-field digital mammography (FFDM) reduces recall rates and increases cancer detection rates relative to FFDM alone. Synthetic mammography is a 2-dimensional reconstructed image, using the dataset derived from the DBT acquisition, without requiring additional radiation dose. Collecting information from patients' medical records may help doctors analyze the characteristics, utility, and impact of synthetic mammography to compared to FFDM.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study compares two types of mammography (breast X-ray imaging) to see how well radiologists interpret them: traditional full-field digital mammography (FFDM) versus newer synthetic 2D mammography generated from a 3D scan. The goal is to see if the synthetic version is just as accurate and whether it can replace the traditional approach. **You may be eligible if...** - You are a female patient 18 or older - You are having a routine mammogram at a breast imaging center **You may NOT be eligible if...** - Your mammogram images have technical errors, missing views, or labeling problems that make them unusable for analysis Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERElectronic Health Record Review

Review of medical records and past imaging examinations


Locations(1)

M D Anderson Cancer Center

Houston, Texas, United States

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NCT05056818


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