RecruitingPhase 4NCT05061732
Helicobacter Pylori Eradication and Follow-up
Helicobacter Pylori Eradication and Follow-up in Zhongshan Hospital
Sponsor
Shanghai Zhongshan Hospital
Enrollment
4,447 participants
Start Date
Sep 30, 2021
Study Type
INTERVENTIONAL
Conditions
Summary
This randomized controlled clinical trial will estimate the eradication efficacy of different therapy for Helicobacter pylori treatment. The completion of this trial will expand new therapy for the treatment of Helicobacter pylori, which can not only ensure clinical efficacy, but also reduce the use of antibiotics.
Eligibility
Min Age: 18 YearsMax Age: 75 Years
Inclusion Criteria3
- Participate in the trial voluntarily, fully understand the trial, and sign the informed consent form (ICF).
- -75 years old on the day of signing the ICF.
- Helicobacter pylori infection confirmed by 13C-urea breath test or rapid urease test.
Exclusion Criteria8
- Patients with severe heart, lung, kidney, liver, blood, nerve, endocrine, and psychiatric diseases.
- Subjects or guardians refused to participate in the trial.
- Alcohol and/or drugs Abuse (addiction or dependence) or poor compliance with doctor's judgment.
- Have taken antibiotics, bismuth, proton pump inhibitors or Chinese traditional medicine 4 weeks before treatment.
- Pregnant or lactating women.
- Active peptic ulcer.
- allergic to drugs used in the trial.
- any other circumstances that are not suitable for recruitment.
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Interventions
DRUGRabeprazole
20mg bid
DRUGBismuth potassium citrate
0.6g bid
DRUGMetronidazole
0.4g qid
DRUGClarithromycin
0.5g bid
DRUGLevofloxacin
0.5g qd
DRUGAmoxicillin
1g tid
DRUGMetronidazole
0.4g tid
DRUGDoxycycline
0.1g bid
DRUGTetracycline
0.5g qid
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05061732
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