RecruitingNCT05062707

Early Ageing During Therapy in AYA Cancer Patients

Longitudinal Assessment of Therapy-related Early Ageing in Adolescent and Young Adult (AYA) Cancer Patients


Sponsor

University Medical Center Groningen

Enrollment

120 participants

Start Date

Feb 10, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

Longitudinal cohort study; measurements before start of systemic therapy and one year later.


Eligibility

Min Age: 18 YearsMax Age: 39 Years

Plain Language Summary

Simplified for easier understanding

This study looks at whether cancer treatment causes "early ageing" in young adults (aged 18–39) diagnosed with cancer. Researchers will measure biological age markers in the blood and track physical and cognitive changes over time to understand the long-term effects of chemotherapy and other treatments. **You may be eligible if...** - You are aged 18–39 at the time of your cancer diagnosis - You have a confirmed diagnosis of one of: leukemia, lymphoma (Hodgkin's or non-Hodgkin's), testicular cancer, osteosarcoma, Ewing sarcoma, breast cancer, or cervical cancer - You are scheduled to start systemic treatment (chemotherapy, surgery, radiation, antibodies) with curative intent **You may NOT be eligible if...** - You will be treated with immune checkpoint inhibitors or anti-angiogenesis targeted therapies - You previously received systemic treatment or radiation for a prior cancer (minor exceptions apply) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREBlood sampling

Study measurements will be performed twice and consist of blood withdrawal and physical examination (weight, height, waist-hip ratio, and blood pressure).


Locations(1)

University Medical Center Groningen

Groningen, Netherlands

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NCT05062707


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