Perform Humeral System Study

This study follows patients who receive a shoulder replacement using the Perform Humeral System, a specific shoulder arthroplasty implant. Researchers will collect data on safety, how well the implant performs, and how patients' quality of life and shoulder function improve over time. You may be eligible if: - You are 18 years or older - You are scheduled for shoulder replacement surgery (arthroplasty) using this specific implant - You are willing to comply with all study visits and procedures - You meet the clinical indications for shoulder arthroplasty You may NOT be eligible if: - You have an active local or systemic infection, or bone infection (osteomyelitis) - You have poor bone quality that could result in implant failure or fracture - You have significant nerve damage (brachial plexus injury) or neuromuscular disease - You have a known allergy to any materials in the implant - You have metabolic disorders that impair bone formation - You are pregnant - You are planning a two-stage surgery procedure Talk to your doctor to see if this trial is right for you.