Avascular Necrosis Clinical Trials

23 recruitingLast updated: June 18, 2026

There are 23 actively recruiting avascular necrosis clinical trials across 13 countries. Studies span Not Applicable, Phase 2. Top locations include Rochester, Minnesota, United States, Portland, Oregon, United States, Baltimore, Maryland, United States. Updated daily from ClinicalTrials.gov.


Avascular Necrosis Trials at a Glance

23 actively recruiting trials for avascular necrosis are listed on ClinicalTrialsFinder across 6 cities in 13 countries. The largest study group is Not Applicable with 10 trials, with the heaviest enrollment activity in Rochester, Portland, and Baltimore. Lead sponsors running avascular necrosis studies include Medacta International SA, Zimmer Biomet, and DePuy Orthopaedics.

Browse avascular necrosis trials by phase

Treatments under study

About Avascular Necrosis Clinical Trials

Looking for clinical trials for Avascular Necrosis? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Avascular Necrosis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Avascular Necrosis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 23 trials

Recruiting
Not Applicable

EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))

Rheumatoid ArthritisOsteoarthritisTraumatic Arthritis+3 more
DePuy Orthopaedics118 enrolled5 locationsNCT06631638
Recruiting
Not Applicable

Safety and Effectiveness of the HIT Reverse HRS

Degenerative Joint DiseaseOsteoarthritis, HipAvascular Necrosis of Hip+1 more
Hip Innovation Technology288 enrolled6 locationsNCT05357378
Recruiting
Not Applicable

Clinical Transformation of Bone Reconstruction With Autologous Bone Marrow Mesenchymal Stem Cells in Vitro to Repair Avascular Necrosis of Femur Head

Avascular Necrosis of Femur Head
The First Affiliated Hospital of Xinxiang Medical College30 enrolled1 locationNCT07101562
Recruiting

RETRO-PROSPECTIVE POSTMARKET CLINICAL STUDY FOR FX SHOULDER SOLUTIONS SHOULDER SYSTEMS

Glenohumeral OsteoarthritisAvascular Necrosis of the Head of HumerusInflammatory Arthritis+4 more
FX Solutions1,004 enrolled22 locationsNCT07558590
Recruiting

Talus Replacement Registry

Avascular Necrosis of the Talus
Kyle Schweser MD50 enrolled1 locationNCT03965143
Recruiting
Phase 2

Alendronate for Osteonecrosis in Adults With Sickle Cell Disease

Sickle Cell DiseaseOsteonecrosisAvascular Necrosis+2 more
University of California, Davis30 enrolled1 locationNCT06016634
Recruiting
Not Applicable

Marrow Cellution™ vs. Traditional BMA Harvest Project

Hip ArthropathyAvascular Necrosis of BoneSubchondral Cysts
Ohio State University6 enrolled1 locationNCT06388993
Recruiting

Observational Study to Evaluate Long-Term Outcome in Hip Hemiarthroplasty

Hip FracturesOsteoarthritis, HipAvascular Necrosis of Hip+2 more
Corin368 enrolled4 locationsNCT05686278
Recruiting

Perform Humeral System Study

Osteoarthritis ShoulderRotator Cuff Tear ArthropathyAvascular Necrosis+1 more
Stryker Trauma and Extremities300 enrolled10 locationsNCT05067543
Recruiting
Not Applicable

Influence of Antiseptic Washes on Wound Healing Complications After THA

hip osteoarthritisAvascular Necrosis of Femur Head
F. Johannes Plate420 enrolled2 locationsNCT07104084
Recruiting

Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)

Rheumatoid ArthritisOsteoarthritis, KneePolyarthritis+6 more
Zimmer Biomet760 enrolled16 locationsNCT05787821
Recruiting
Not Applicable

Autologous Bone Marrow Aspirate Treatment for Early-Stage Osteonecrosis

Osteonecrosis of the Femoral HeadAvascular Necrosis of the Femoral Head
Johns Hopkins University192 enrolled10 locationsNCT06123481
Recruiting

Z1 Hip System: Post-Market Clinical Follow Up Study

Avascular Necrosis of the Femoral Headhip osteoarthritisAcute Traumatic Fracture of the Femoral Head or Neck
Zimmer Biomet150 enrolled2 locationsNCT07104279
Recruiting

Clinical and Radiological Outcomes of Medacta Shoulder System FR

FractureRheumatoid Arthritis ShoulderPrimary Osteoarthritis+4 more
Medacta International SA200 enrolled1 locationNCT05926622
Recruiting

The Medacta International SMS Post-Marketing Surveillance Study

Traumatic ArthritisAvascular Necrosis of the Femoral HeadArthrosis+2 more
Medacta International SA550 enrolled4 locationsNCT02748408
Recruiting
Not Applicable

Catalyst CSR Shoulder System for Semi or Total Shoulder Arthroplasty

Osteoarthritis ShoulderAvascular Necrosis of the Head of HumerusRheumatoid Arthritis Shoulder
Catalyst OrthoScience90 enrolled3 locationsNCT04968405
Recruiting
Not Applicable

G7 Acetabular System With Vivacit-E or Longevity Liner PMCF Study

Osteoarthritis, HipTotal Hip ArthroplastyDegenerative Joint Disease of Hip+5 more
Zimmer Biomet300 enrolled11 locationsNCT04754087
Recruiting
Not Applicable

Hydrogel Coating to Reduce Post-surgical Infection After Joint Arthroplasty

ArthritisAvascular NecrosisTraumatic Arthritis
Medacta International SA56 enrolled1 locationNCT05679232
Recruiting

Patient Specific Talus Spacer Post Approval Study

Avascular Necrosis of the Talus
Paragon 2850 enrolled6 locationsNCT05364606
Recruiting

Multicentre SMS Study - FR

hip osteoarthritisDysplasia of Hip JointTraumatic Arthritis of Hip+1 more
Medacta International SA260 enrolled1 locationNCT06640764