RecruitingNCT05075252

Re-assessment of Appendicitis Evaluation During Laparoscopic Appendectomy, Peritoneal Irrigation During Laparoscopic Appendectomy Does the Grade of Contamination Matter?

REsiDENT1 (Re-assessment of Appendicitis Evaluation During Laparoscopic Appendectomy: Do we End a Non-standardized Treatment Approach and Habit?): Peritoneal Irrigation During Laparoscopic Appendectomy-Does the Grade of Contamination Matter? A Prospective Multicenter Resident-based Evaluation of a New Classification System

Sponsor

Niguarda Hospital

Enrollment

1,067 participants

Start Date

Oct 1, 2019

Study Type

OBSERVATIONAL

Conditions

Appendectomy Appendicitis

Summary

Type: prospective observational multicenter trial. Population of interest: adult patients undergoing laparoscopic appendectomy for acute appendicitis. Hypothesis : laparoscopic lavage during laparoscopic appendectomy is a practice that should be used in selected patients according to the intraperitoneal grade of contamination and grade of appendicitis. Nonregulated use of laparoscopic lavage cannot be considered superior to suction only considering recent evidence. Few RCT available addressing this issue are available, but any with a high methodological quality. Aim: The aim of this study is to investigate the impact of laparoscopic lavage during laparoscopic appendectomy on the postoperative incidence of intrabdominal abscesses, stratifying patients in different clusters according to a defined classification considering the intraperitoneal contamination and grade of appendicitis.

Eligibility

Min Age: 18 YearsMax Age: 69 Years

Inclusion Criteria3

Patients between 18 and 69 years old
Surgical laparoscopic approach for AA
Intra-operative and histological diagnosis of AA

Exclusion Criteria7

Patients < 18 years old or > 69 years old
Previous appendectomy
Previous appendicitis treated conservatively
Open approach for surgery or intra-operative conversion
Co-existence of other intra-abdominal infections (IAI)
Patients with immunodeficiency
Patients treated with steroid, immunosuppressant, or CHT within previous 6 months

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Interventions

PROCEDURElaparoscopic lavage

This study aims to investigate the impact of laparoscopic lavage on the incidence of postoperative abscesses stratifying patients on the grade of appendicitis and peritoneal contamination.