Appendicitis Clinical Trials

28 recruiting

Frequently Asked Questions

Common questions about Appendicitis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 32 trials

Recruiting
Not Applicable

Same Day Ambulatory Appendectomy (SAMBA)

Appendicitis
Centre Hospitalier Universitaire de Nice1,400 enrolled33 locationsNCT05691348
Recruiting
Phase 4

Fast Track Therapeutic Model in Acute Complicated Appendicitis in Pediatrics

Laparoscopic AppendectomyComplicated AppendicitisPeriappendicular Abscess
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau772 enrolled7 locationsNCT05761080
Recruiting
Not Applicable

Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients

AppendectomyAppendicitisAppendicitis Acute
Ann & Robert H Lurie Children's Hospital of Chicago500 enrolled4 locationsNCT06395636
Recruiting

Clinical Study of PEG Bowel Preparation in Appendectomy Patients

AppendicitisAppendicitis Acute
Huaping Xie10 enrolled1 locationNCT07478029
Recruiting
Phase 1

Precision Antibiotic Dosing for Appendectomy

Appendicitis (Diagnosis)
University of Michigan46 enrolled1 locationNCT06860802
Recruiting
Phase 4

APPI-Cost Trial for Perforated Appendicitis

Perforated Appendicitis
The University of Texas Health Science Center, Houston346 enrolled1 locationNCT06705842
Recruiting
Not Applicable

The Impact of a Diagnostic Strategy for Acute Appendicitis in Children With Acute Abdominal Pain in Primary Care

Appendicitis AcuteAcute Abdomen in Children
University Medical Center Groningen566 enrolled1 locationNCT06762275
Recruiting
Not Applicable

Benefit of Hypnosis on Smartphone for Acute Post-operative Pain (HYPNO-APP)

Appendicitis With Peritonitis
Centre Hospitalier Universitaire de Nice20 enrolled1 locationNCT05854914
Recruiting
Not Applicable

Operative Versus Non-Operative Management for Appendicitis With Abscess or Phlegmon

Appendicitis
Yale University180 enrolled1 locationNCT04168866
Recruiting
Not Applicable

Results of Laparoscopic Appendectomy With Application of Clips Versus Ligature for Stump Closure

Appendicitis
Sohag University80 enrolled1 locationNCT07115303
Recruiting
Not Applicable

PAINED: Project Addressing INequities in the Emergency Department

AppendicitisPainFractures, Bone+1 more
Children's National Research Institute22,032 enrolled1 locationNCT05488080
Recruiting

Prevention of Postoperative Hernias in Emergency Surgery

IleusAppendicitis AcuteCholecystitis, Acute+3 more
Jan Kochanowski University500 enrolled1 locationNCT06815822
Recruiting
Not Applicable

Early vs Conventional Enteral Nutrition After Uncomplicated Paediatric Open Appendectomy

Uncomplicated Acute Appendicitis in Children
Shaikh Zayed Hospital, Lahore88 enrolled1 locationNCT07016919
Recruiting
Not Applicable

Low-dose Contrast Media for Low-kVp Abdomen CT

Appendicitis Acute
Bohyun Kim292 enrolled1 locationNCT05878665
Recruiting
Phase 4

Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSF

Appendicitis
University of California, San Francisco145 enrolled1 locationNCT05966454
Recruiting
Not Applicable

Enhanced Recovery After Surgery (ERAS) for Complicated Appendicitis

Appendicitis AcuteAppendicitis PerforatedAppendicitis With Perforation+2 more
Cedars-Sinai Medical Center20 enrolled1 locationNCT06948071
Recruiting

A Global Prospective Cohort Study on Outcomes of Appendicectomy for Appendicitis

AppendectomyAppendicitis
University of Birmingham14,000 enrolled7 locationsNCT06774001
Recruiting
Not Applicable

Protocol Based Selective Imaging Versus Routine Computed Tomography or Ultrasound in Suspected Appendicitis

Appendicitis
Helsinki University Central Hospital900 enrolled3 locationsNCT06083064
Recruiting
Not Applicable

Complex and Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure (CASA RELAX)

Appendicitis
University of Louisville50 enrolled2 locationsNCT05838248
Recruiting
Not Applicable

Transumbilical Laparoscopic Appendectomy

AppendicitisSurgical Site Infection
Necmi Kadıoğlu Hospital100 enrolled1 locationNCT06177418