Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study

This study is testing whether starting the drug sirolimus (an mTOR inhibitor) in babies with tuberous sclerosis complex (TSC) — before any seizures occur — can prevent epilepsy from ever developing. **You may be eligible if...** - Your baby has a confirmed diagnosis of tuberous sclerosis complex (TSC) based on genetic or clinical criteria - Your baby is 6 months old or younger (no older than 7 months at the start of treatment) - If premature, the corrected gestational age is at least 39 weeks - Your baby has NOT yet had any seizures (including those detectable only on a brain activity monitor) **You may NOT be eligible if...** - Your baby has already had any seizures - Your baby has already been treated with anti-seizure medications or mTOR inhibitors - Your baby has other serious health conditions that might interfere with the study Talk to your doctor to see if this trial is right for you.