RecruitingPhase 1NCT06355232

Covid-19 and Influenza Oral Vaccine Study

A Binded, Randomised, Controlled Cross-over Trial to Assess the Safety and Efficacy of Mucosal Covid-19 and Influenza Vaccines


Sponsor

Vaxine Pty Ltd

Enrollment

100 participants

Start Date

May 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of the current study is to assess the effectiveness of protein-based COVID-19 or influenza vaccines when given individually or together via oral/ sublingual mucosal route instead of intramuscular delivery. The comparator will be a seasonal influenza vaccine which will also be administered with Advax-CpG adjuvant via the oral route. This study will use a cross-over design and everyone in the study will over a space of about 4 months receive both the COVID-19 and influenza vaccines.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called Covid-19 vaccine and a biological treatment called Influenza vaccine for people with influenza, human and covid19 infection. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALCovid-19 vaccine

Recombinant SARS-CoV-2 spike protein with Advax-CpG55.2 adjuvant

BIOLOGICALInfluenza vaccine

Inactivated seasonal influenza vaccine with Advax-CpG55.2 adjuvant


Locations(1)

ARASMI

Adelaide, South Australia, Australia

View Full Details on ClinicalTrials.gov

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NCT06355232


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