RecruitingNot ApplicableNCT05150145

Radiotherapy or Observation of Liver Metastases in Small Cell Lung Cancer

A Prospective Phase II Randomized Clinical Study of Radiotherapy or Observation of Liver Metastases for Small Cell Lung Cancer.


Sponsor

Guizhou Medical University

Enrollment

66 participants

Start Date

Apr 30, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of this randomized study is to investigate local tumor control,survival outcomes and complications on patients of liver metastasis in small cell lung cancer.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing radiation therapy to observation (watchful waiting) for liver metastases in patients with small cell lung cancer (SCLC) who are receiving chemotherapy. The goal is to see whether adding radiation to the liver improves survival and outcomes. **You may be eligible if...** - You are between 18 and 70 years old - You have been newly diagnosed with small cell lung cancer that has spread to the liver - This is your first treatment (no prior thoracic radiation or surgery) - Your overall health is good enough for treatment (ECOG performance status 0–2) - Your blood counts and organ function are within acceptable ranges - Your expected survival is more than 3 months **You may NOT be eligible if...** - You have a history of mental illness - You have another active cancer - You have an active bacterial, fungal, or viral infection requiring IV antibiotics - You have serious heart disease, uncontrolled high blood pressure, or a recent heart attack - You have poorly controlled diabetes - You are pregnant or breastfeeding - You have a history of hepatitis or liver cirrhosis Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONRadiotherpy will be performed to thoracic and liver metastasis after chemotherapy.

Intensity modulated radiotherapy will be performed to liver metastasis and thoracic SCLC patients who achieved CR or PR after chemotherapy .


Locations(1)

The affiliated hospital of Guizhou medical university

Guiyang, Guizhou, China

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NCT05150145


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