RecruitingNot ApplicableNCT05156112

OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit

Examining Early Intervention Obstructive Sleep Apnea Treatment on Long-Term Outcomes in Veterans With SUD/PTSD in a Residential Treatment Program

Sponsor

VA Office of Research and Development

Enrollment

194 participants

Start Date

Jan 2, 2023

Study Type

INTERVENTIONAL

Conditions

Obstructive Sleep Apnea Substance Use Disorder Post Traumatic Stress Disorder Residential Treatment Program

Summary

Substance use disorder (SUD) and posttraumatic stress disorder (PTSD) frequently co-occur and having both disorders is associated with greater psychological and functional impairment than having either disorder alone. This is especially true in residential settings where both disorders are more severe than outpatient settings. Obstructive sleep apnea (OSA) is highly comorbid with both disorders and untreated OSA is associated with worse functional impairment across multiple domains, worse quality of life, worse PTSD, higher suicidal ideation, and higher substance use and relapse rates. Treating OSA with evidence-based positive airway pressure (PAP) in Veterans with SUD/PTSD on a residential unit is a logical way to maximize treatment adherence and treatment outcomes. This study compares OSA treatment while on a SUD/PTSD residential unit to a waitlist control group. The investigators hypothesize that treating OSA on the residential unit, compared to the waitlist control, will have better functional, SUD, and PTSD outcomes.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether treating sleep apnea with PAP therapy (a breathing machine worn at night) in veterans who have both PTSD and a substance use disorder (SUD) can improve their recovery outcomes during a residential treatment program. Sleep problems are common and often worsen PTSD and addiction recovery. **You may be eligible if...** - You are a U.S. military veteran or National Guard/Reserve member, at least 18 years old - You have a diagnosis of PTSD confirmed by a clinical assessment - You have a substance use disorder (at least 20 days of use in the past 90 days) - You have been diagnosed with obstructive sleep apnea (AHI of 5 or more events per hour) - You are currently in the PTSD track of a residential treatment program - You are able to read and write English **You may NOT be eligible if...** - You have central sleep apnea (rather than obstructive sleep apnea) - You are already using a PAP device for sleep apnea - The program's medical staff advises against your participation - You have severe cognitive impairment - You have a history of psychosis or mania not caused by substance use Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEPositive Airway Pressure Device

Each PAP treatment initiation meeting will include 1) mask fitting; 2) psycho-education to what to expect and reviewing PAP machine problem solving; and 3) setting up correct PAP treatment (e.g., auto PAP or in rare conditions, bi-level PAP).