Effect of Extended Cannabis Abstinence on PTSD Symptoms

This study is examining how stopping cannabis use for an extended period affects symptoms of PTSD (post-traumatic stress disorder) in people who use cannabis heavily and are also living with PTSD. **You may be eligible if...** - You are 18–55 years old - You have a moderate or severe cannabis use disorder - You have been diagnosed with current PTSD (symptoms in the last 30 days) - You have been taking antidepressant medication for at least 1 month - You can communicate in English and provide written consent **You may NOT be eligible if...** - You have a severe or unstable medical condition - You have schizophrenia, schizoaffective disorder, bipolar disorder, or active psychosis - You are at risk of suicide - You have chronic pain that significantly interferes with your daily life Talk to your doctor to see if this trial is right for you.