Cannabis Use Clinical Trials

80 recruitingLast updated: June 18, 2026

There are 80 actively recruiting cannabis use clinical trials across 11 countries. Studies span Not Applicable, Phase 2, Phase 1, Early Phase 1, Phase 4, Phase 3. Top locations include Charleston, South Carolina, United States, Aurora, Colorado, United States, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


Cannabis Use Trials at a Glance

80 actively recruiting trials for cannabis use are listed on ClinicalTrialsFinder across 6 cities in 11 countries. The largest study group is Not Applicable with 43 trials, with the heaviest enrollment activity in Charleston, Aurora, and Boston. Lead sponsors running cannabis use studies include Medical University of South Carolina, Yale University, and University of Colorado, Denver.

Browse cannabis use trials by phase

Treatments under study

About Cannabis Use Clinical Trials

Looking for clinical trials for Cannabis Use? There are currently 41 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cannabis Use trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cannabis Use clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 80 trials

Recruiting
Phase 2

Longitudinal Outpatient Treatment for Cannabis Use Disorder

Cannabis Use Disorder
University of Colorado, Boulder165 enrolled1 locationNCT06107062
Recruiting
Not Applicable

Neuroimaging of Adolescent Cannabis Use Treatment

Cannabis withdrawalSubstance Use DisordersCannabis Use+23 more
Indiana University80 enrolled1 locationNCT07340554
Recruiting
Not Applicable

Joint Effort 2.0 : Evaluation Among General Population

Cannabis Use
Centre hospitalier de l'Université de Montréal (CHUM)110 enrolled1 locationNCT07524985
Recruiting
Not Applicable

Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use

Depression - Major Depressive DisorderMental DisorderCannabis Use Disorder
Massachusetts General Hospital80 enrolled1 locationNCT06878859
Recruiting
Not Applicable

Precision Brain Stimulation to Reduce Cannabis Craving in Schizophrenia

SchizophreniaCannabis UsePsychosis+1 more
Vanderbilt University Medical Center100 enrolled1 locationNCT07196462
Recruiting
Not Applicable

Evaluating the Impact of Psychotherapeutic Advertising Claims on Cannabis Purchasing

DepressionAnxietyCannabis Use
Trustees of Dartmouth College2,000 enrolled1 locationNCT07216911
Recruiting
Not Applicable

Investigating the Neural Correlates of Cognitive Function in Psychosis Patients and Non-Psychiatric Controls With Cannabis Use

Cognitive DysfunctionPsychotic DisordersCannabis Use+5 more
Douglas Mental Health University Institute134 enrolled1 locationNCT05445180
Recruiting
Not Applicable

Effect of Acute Exercise on Cognitive Functions and Blood Markers of Brain Plasticity in Regular Chronic Cannabis Users

Cannabis User
University Hospital, Lille60 enrolled1 locationNCT06081218
Recruiting
Phase 2

Effect of Semaglutide on Cannabis Use in Adults With Cannabis Use Disorder

Cannabis Use DisorderCannabis DependenceCannabis Abuse+2 more
Anders Fink-Jensen, MD, DMSci100 enrolled1 locationNCT07523633
Recruiting
Not Applicable

Cannabis and Processing Emotions Study

Cannabis Use Disorder, Severe
Auburn University24 enrolled1 locationNCT06907979
Recruiting
Phase 2

Sex Differences in Neurobehavioral Response to THC

Cannabis Use Disorder
Medical University of South Carolina40 enrolled1 locationNCT07225777
Recruiting
Not Applicable

Environment and Lung Cancer

Cannabis Use
Centre Chirurgical Marie Lannelongue150 enrolled3 locationsNCT05119244
Recruiting
Phase 2

A Study of Cannabidiol in Young Adult Cannabis Users

Cannabis Use Disorder
University of Colorado, Denver200 enrolled1 locationNCT06569394
Recruiting
Phase 2

Cannabidiol and Cannabis Concentrate Users

Cannabis Use Disorder
University of Colorado, Denver120 enrolled1 locationNCT06575751
Recruiting
Not Applicable

Stress and Pain in People Living With HIV

PainDepressionStress+2 more
Yale University120 enrolled1 locationNCT06784908
Recruiting
Not Applicable

Neural and Psychiatric Consequences of Cannabis Use in Adolescents

DepressionCannabis Use
University of Miami280 enrolled2 locationsNCT06941298
Recruiting
Not Applicable

RS-tDCS for Cannabis Use Disorder: The C.A.R.E.S. Initiative

Cannabis Use Disorder
NYU Langone Health46 enrolled1 locationNCT07184983
Recruiting
Phase 1

The Impact of Product Formulation on the Pharmacokinetics and Pharmacodynamics of Cannabis Edibles

Cannabis Use
Johns Hopkins University80 enrolled1 locationNCT05602649
Recruiting
Phase 1

Effect of Cannabis on E-Cigarette Use Behavior

Cannabis UseTobacco UseElectronic Cigarette Use
Johns Hopkins University100 enrolled1 locationNCT06609109
Recruiting
Not Applicable

A Brief Intervention for Cannabis Use

Cannabis Use Disorder
Medical University of South Carolina62 enrolled1 locationNCT06395389