Cannabis Use Clinical Trials

11 recruiting

Frequently Asked Questions

Common questions about Cannabis Use clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 20 trials

Recruiting
Not Applicable

Cannabis, Linked Emotions, and Adolescent Risk Study

DepressionSuicidal IdeationCannabis Use+1 more
Massachusetts General Hospital200 enrolled1 locationNCT06576076
Recruiting
Not Applicable

Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use

Depression - Major Depressive DisorderMental DisorderCannabis Use Disorder
Massachusetts General Hospital80 enrolled1 locationNCT06878859
Recruiting
Not Applicable

Precision Brain Stimulation to Reduce Cannabis Craving in Schizophrenia

SchizophreniaCannabis UsePsychosis+1 more
Vanderbilt University Medical Center100 enrolled1 locationNCT07196462
Recruiting

SV2 PET Imaging With [11C]APP311

HealthyCannabis Use DisorderSchizophrenia and Other Psychotic Disorders
Yale University250 enrolled1 locationNCT03995121
Recruiting
Phase 1Phase 2

Mitigating PTSD-CUD After Sexual Assault

Cannabis Use DisorderPosttraumatic Stress Disorder
University of Nevada, Las Vegas68 enrolled6 locationsNCT05989841
Recruiting
Phase 1

HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)

Cannabis UseAlcohol DrinkingHIV+1 more
Yale University100 enrolled1 locationNCT06513819
Recruiting
Phase 1

Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use

Depression, AnxietyAnxietyDepression - Major Depressive Disorder+1 more
Trustees of Dartmouth College15 enrolled1 locationNCT06920238
Recruiting

Longitudinal Study of Xenon-129 MRI Imaging Effects of Cannabis Smoking

Cannabis UseCannabis SmokingMarijuana Smoking+1 more
Western University, Canada200 enrolled1 locationNCT03909477
Recruiting
Not Applicable

The Neural Underpinnings of Depression and Cannabis Use in Young People Living With HIV

DepressionHIVCannabis Use Disorder
University of Miami280 enrolled1 locationNCT05453513
Recruiting
Phase 2

Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders

Cannabis UseBipolar DisorderSchizoaffective Disorder, Bipolar Type+5 more
Medical University of South Carolina68 enrolled1 locationNCT05064319
Recruiting
Phase 1

Genetics of Cannabis Use Disorder and Cannabinoid Response in Humans

SchizophreniaCannabis Use Disorder
Yale University215 enrolled1 locationNCT06058702
Recruiting
Not Applicable

Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use

SchizophreniaCannabis UseMajor Depressive Disorder+3 more
Nova Scotia Health Authority120 enrolled1 locationNCT03601026
Recruiting
Not Applicable

Neural and Psychiatric Consequences of Cannabis Use in Adolescents

DepressionCannabis Use
University of Miami280 enrolled2 locationsNCT06941298
Recruiting
Phase 2

Psilocybin in the Treatment of Cannabis Use Disorder: A-Proof-of-Concept Study

Cannabis Use Disorder, ModerateCannabis Use Disorder, Severe
McMaster University16 enrolled1 locationNCT06225232
Recruiting
Not Applicable

Extended Effects of Cannabis Abstinence on Clinical Symptoms and Cognition in Depression

Cognitive ImpairmentCannabis UseMajor Depressive Disorder
Centre for Addiction and Mental Health52 enrolled1 locationNCT04935619
Recruiting
Not Applicable

Stress and Pain in People Living With HIV

PainDepressionStress+2 more
Yale University120 enrolled1 locationNCT06784908
Recruiting

Youth Experiences and Health Study

Psychotic DisordersCannabis UseTrauma, Psychological+2 more
Finnish Institute for Health and Welfare1,000 enrolled3 locationsNCT03332966
Recruiting
Not Applicable

Investigating the Neural Correlates of Cognitive Function in Psychosis Patients and Non-Psychiatric Controls With Cannabis Use

Cognitive DysfunctionPsychotic DisordersCannabis Use+5 more
Douglas Mental Health University Institute134 enrolled1 locationNCT05445180
Recruiting
Not Applicable

Effect of Extended Cannabis Abstinence on PTSD Symptoms

Comorbidities and Coexisting ConditionsCannabis UsePTSD+1 more
Centre for Addiction and Mental Health24 enrolled1 locationNCT05162651
Recruiting
Not Applicable

RCT Comparing Avatar Intervention to Supportive Intervention to Reduce Cannabis Use in Patients With Psychotic Disorders

Mental Health DisorderPsychotic DisordersCannabis Use Disorder
Ciusss de L'Est de l'Île de Montréal150 enrolled1 locationNCT05704582