Multidisciplinary Expert System for the Assessment & Management of Complex Brain Disorders
Neurological Institute of Athens
350 participants
Apr 1, 2021
OBSERVATIONAL
Conditions
Summary
The Multidisciplinary Expert System for the Assessment \& Management of Complex Brain Disorders (MES-CoBraD) is an interdisciplinary project combining Real-World Data (RWD) from multiple clinical and consumer sources through comprehensive, cost-efficient, and fast protocols towards improving diagnostic accuracy and therapeutic outcomes in people with Complex Brain Disorders (CoBraD), as reflected in Neurocognitive (Dementia), Sleep, and Seizure (Epilepsy) disorders and their interdependence. It brings together internationally recognized experts in medicine, engineering, computer science, social health science, law, and marketing and communication from across Europe, and combines clinical information and scientific research in CoBraD with technical innovation in secure data-sharing platforms, artificial intelligence algorithms, and expert systems of precision and personalized care, with a primary focus on improving the quality of life of patients, their caregivers, and the society at large. It leverages RWD from diverse CoBraD populations across cultural, socioeconomic, educational, and health system backgrounds, with special attention on including vulnerable populations and minorities in an equitable manner and engaging key stakeholders to maximize project impact.
Eligibility
Inclusion Criteria1
- All participants willing to undergo comprehensive assessment who visit one of three clinics (Epilepsy, Neurocognitive disorders, and Sleep Disorders), and healthy volunteers
Exclusion Criteria1
- participant disinterest
Interventions
concurrent overnight sleep study with full electroencephalography (in-lab or at home)
blood or CSF collection for analyses of neurodegenerative, inflammatory, and, per condition, genetic information
paper and pencil, as well as tablet based cognitive testing
week long actigraphy assessment with concurrent sleep diary acquisition
standard clinical assessment by an expert clinician in the respective field of brain disorders
Locations(4)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05171725