RecruitingNCT05189262

Cardiopulmonary Bypass Induced Red Blood Cell Lysis

Extra-Cellular Hemoglobin, Organ Injury in Extended Cardiopulmonary Bypass

Sponsor

University of Maryland, Baltimore

Enrollment

150 participants

Start Date

Mar 22, 2022

Study Type

OBSERVATIONAL

Conditions

Cardiac Surgery Cardiopulmonary Bypass Kidney Injury, Acute

Summary

Studying the dynamics of red blood cell lysis, pfH, protective proteins and organ injury, limits will be set for safe levels of pfH following the use of CPB. These results will be compared to existing laboratory-based methods for determining red blood cell damage to predict CPB assist device safety. Further, results from the studies described in this proposal will help develop therapeutic strategies to benefit patients by early detection of pfH and clearance protein levels that occur during CPB.

Eligibility

Min Age: 18 YearsMax Age: 88 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Blood and urine collection for people with cardiac surgery, cardiopulmonary bypass, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 88 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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