Nutrition to Optimize, Understand, and Restore Insulin Sensitivity in HIV for Oklahoma
University of Oklahoma
234 participants
Oct 9, 2020
INTERVENTIONAL
Conditions
Summary
The NOURISH-OK Study will identify how food insecurity contributes to insulin resistance, an important surrogate marker of many co-morbidities in HIV disease, using an integrated framework to identify key leverage points for insulin resistance. Drawing from these pathways, this study will adapt and evaluate a community-driven, science-informed "food as medicine" intervention designed to lower insulin resistance through healthy food access, food utilization skills, and other self-care behaviors. Knowledge gained from this study can benefit those living with HIV through the prevention and more effective management of pre-diabetes, diabetes, obesity, and non-alcoholic fatty liver disease.
Eligibility
Inclusion Criteria4
- HIV-positive with income \<400% federal poverty level
- at least 1 risk factor for insulin resistance per the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (i.e., overweight/obesity, age 45 yrs or older, immediate family member with diabetes, non-white race, physical inactivity, history of gestational diabetes, history of heart disease or stroke, diagnosis of polycystic ovarian syndrome, high blood pressure, high cholesterol, or hepatitis C virus antibody positivity
- using antiretroviral therapy for at least 6 months
- English-speaking
Exclusion Criteria4
- participating in another health-related research study
- receiving treatment for a terminal or other serious illness, such as cancer or end-stage renal failure
- plan to move outside of Oklahoma during the study period
- does not have an address that can accept home-delivered groceries
Interventions
Selection of healthy groceries designed to reduce chronic inflammation and improve insulin resistance with healthy cooking/self-care curriculum
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05208671