RecruitingNCT05221372

ProSpecTive sAmpling in dRiver muTation Pulmonary Oncology Patients on Tyrosine Kinase Inhibitors (START-TKI)

proSpecTive sAmpling in dRiver muTation Pulmonary Oncology Patients on Tyrosine Kinase Inhibitors


Sponsor

Erasmus Medical Center

Enrollment

1,300 participants

Start Date

Feb 2, 2017

Study Type

OBSERVATIONAL

Conditions

Summary

The study is perfomed with adult patients with non-small cell lung cancer treated with tyrosine kinase inhibitor. The objective is to collect repeated samples of blood from patients (starting) on a tyrosine kinase inhibitor, for liquid mutation testing, and pharmacokinetic analysis.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Age ≥ 18 years
  • Able to understand the written informed and able to give informed consent
  • Locally advanced or metastatic NSCLC with oncogenic driver mutation
  • Treatment with TKI according to standard of care

Exclusion Criteria1

  • Unable to draw blood for study purposes

Locations(1)

Erasmus MC

Rotterdam, Netherlands

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NCT05221372


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