Tyrosine Kinase Inhibitor Clinical Trials

9 recruitingLast updated: May 11, 2026

There are 9 actively recruiting tyrosine kinase inhibitor clinical trials across 5 countries. Studies span Phase 2, Not Applicable, Phase 1, Phase 3, Phase 4. Top locations include Rotterdam, Netherlands, Annecy, France, Arnhem, Netherlands. Updated daily from ClinicalTrials.gov.


Tyrosine Kinase Inhibitor Trials at a Glance

9 actively recruiting trials for tyrosine kinase inhibitor are listed on ClinicalTrialsFinder across 6 cities in 5 countries. The largest study group is Phase 2 with 2 trials, with the heaviest enrollment activity in Rotterdam, Annecy, and Arnhem. Lead sponsors running tyrosine kinase inhibitor studies include Centre Hospitalier Universitaire Dijon, Erasmus Medical Center, and Azienda USL Reggio Emilia - IRCCS.

Browse tyrosine kinase inhibitor trials by phase

Treatments under study

About Tyrosine Kinase Inhibitor Clinical Trials

Looking for clinical trials for Tyrosine Kinase Inhibitor? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Tyrosine Kinase Inhibitor trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Tyrosine Kinase Inhibitor clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting

Innovative Biomarkers of Cardiovascular Complications Associated With Second-generation Bruton Tyrosine Kinase Inhibitor Treatments: a Single-center Cohort Study

Treatment With Second-generation Bruton's Tyrosine Kinase Inhibitors (Acalabrutinib, Zanubrutinib)
Centre Hospitalier Universitaire Dijon100 enrolled1 locationNCT07174141
Recruiting
Not Applicable

The TASTY-training Study

Patients Who Are Treated With Tyrosine Kinase Inhibitors
University Medical Center Groningen90 enrolled11 locationsNCT07258589
Recruiting

A Potential Relationship Between Treatment With Tyrosine Kinase Inhibitors and Erectile Dysfunction in Male Patients With Chronic Myeloid Leukemia

Chronic Myelocytic LeukemiaErectile DysfunctionsCVD - Cardiovascular Disease+1 more
Azienda USL Reggio Emilia - IRCCS350 enrolled1 locationNCT07061145
Recruiting
Phase 4

Firmonertinib Combined With Intrathecal Injection for the Treatment of EGFR Mutant NSCLC With Leptomeningeal Metastases

NSCLCLeptomeningeal MetastasisTyrosine Kinase Inhibitor+1 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology40 enrolled1 locationNCT07092202
Recruiting

Analysis of Circulating Tumor DNA Dynamics to Predict and Monitor Response to TKI in Patients With Advanced NSCLC.

Non-small Cell Lung CancerStage IV Non-Small Cell Lung CancerTyrosine Kinase Inhibitors+2 more
Gene Solutions50 enrolled1 locationNCT06167460
Recruiting
Phase 1Phase 2

A Study of Almonertinib Combined With Palbociclib in Patients With Advanced Solid Tumors Harboring KRAS Mutations

EGFR Tyrosine Kinase Inhibitors Plus Cyclin-dependent Kinase 4/6 Inhibitor
Sun Yat-sen University71 enrolled1 locationNCT06947811
Recruiting
Phase 2

Neoadjuvant Befotertinib Combined Bevacizumab or Platinum-based Double Chemotherapy for Resectable Locally-advanced EGFR Mutation-positive Non-Small Cell Lung Cancer

Non-small Cell Lung CancerAntineoplastic AgentsEGFR+5 more
Peng Zhang60 enrolled1 locationNCT06755684
Recruiting
Phase 3

Discontinuation of TyrosIne Kinase Inhibitors (TKI) in Chronic Myeloid Leukemia (CML) and Impact on the Immune System

Chronic Myeloid LeukemiaTyrosine Kinase Inhibitors
Poitiers University Hospital140 enrolled20 locationsNCT05753384
Recruiting

ProSpecTive sAmpling in dRiver muTation Pulmonary Oncology Patients on Tyrosine Kinase Inhibitors (START-TKI)

Non-small Cell Lung CancerLiquid BiopsyTyrosine Kinase Inhibitor
Erasmus Medical Center1,300 enrolled1 locationNCT05221372