RecruitingNot ApplicableNCT05222594

Computational Neuroscience of Language Processing in the Human Brain


Sponsor

Massachusetts General Hospital

Enrollment

40 participants

Start Date

Apr 2, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

Language is a signature human cognitive skill, but the precise computations that support language understanding remain unknown. This study aims to combine high-quality human neural data obtained through intracranial recordings with advances in computational modeling of human cognition to shed light on the construction and understanding of speech.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Inclusion Criteria3

  • clinical indications to proceed with intracranial monitoring involving the left cerebral hemisphere, as determined by a multidisciplinary epilepsy surgery team
  • the ability to comply with test directions and provide informed consent
  • between ages 18 - 85

Exclusion Criteria1

  • inability to understand or perform the task outlined in the protocol, or who are unwilling or unable to participate

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Interventions

OTHERBehavioral tasks during intracranial monitoring

Participants will listen to sentences and stories while neural data are recorded through electrodes placed for clinical purposes.


Locations(1)

Massachusetts General Hospital

Boston, Massachusetts, United States

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NCT05222594


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