Developing Brain Imaging Analysis Expertise for Personalizing Transcranial Electric Stimulation in Anhedonia Treatment of Patients With Bipolar Depression

This study uses brain imaging and a mild form of brain stimulation (transcranial direct current stimulation, or tDCS) to help personalize treatment for people with bipolar disorder who experience a persistent lack of pleasure or motivation — called anhedonia — even when depression symptoms are mild. **You may be eligible if...** - You have been diagnosed with bipolar disorder - You are experiencing significant anhedonia (lack of enjoyment or motivation) - Your depression symptoms are currently mild **You may NOT be eligible if...** - You have used illicit drugs (other than alcohol or nicotine) in the past month - You have a personality disorder that would interfere with participation - You have a history of epilepsy, traumatic brain injury, or stroke - You have a life-threatening non-psychiatric illness - You have metal plates in your head (which would interfere with tDCS) - You are currently suicidal or severely agitated Talk to your doctor to see if this trial is right for you.