RecruitingNot ApplicableNCT05252039

Goals in Focus: CBT for Motivational Negative Symptoms of Psychosis

Goals in Focus: CBT for Motivational Negative Symptoms of Psychosis - a Randomized-controlled Feasibility Trial


Sponsor

University of Hamburg-Eppendorf

Enrollment

30 participants

Start Date

Mar 1, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

This pilot feasibility trial aims to evaluate the "Goals in Focus" intervention for motivational negative symptoms in people with psychosis. Goals in Focus interventions translate findings of basic clinical research on psychological mechanisms of motivational negative symptoms into a tailored and comprehensive novel psychological treatment program. The current single-blind randomized-controlled study aims to test feasibility and to examine first estimates of the expected effect size of Goals in Focus to inform a subsequent fully-powered RCT. The feasibility data will be used to improve on the trial design and the provision of the "Goals in Focus" intervention where necessary.


Eligibility

Min Age: 16 YearsMax Age: 85 Years

Inclusion Criteria6

  • ICD-10 diagnosis of a schizophrenia spectrum disorder (confirmed by the Structured Clinical Interview for DSM V Clinical Version
  • at least moderate motivational negative symptoms (i.e., scores ≥ 3 (moderate) in two items or ≥ 4 (moderately severe) in one item of the 'motivation and pleasure factor' of the Brief Negative Symptom Scale (BNSS)
  • sufficient skills in German language to participate in psychological therapy
  • capable to engage in weekly therapy sessions of 50-minutes
  • prioritize the reduction of negative symptoms as their current goal for treatment
  • capable to give informed consent to participate in the trial

Exclusion Criteria4

  • being at immediate and serious risk to self or others
  • co-morbid diagnosis of alcohol or substance use disorder
  • intake of Benzodiazepines for \>2 days per week
  • receiving any other psychological treatment aiming to reduce motivational negative symptoms

Interventions

BEHAVIORALGoals in Focus

Goals in Focus (GiF) is a symptom-specific treatment program that targets motivational negative symptoms in patients with schizophrenia-spectrum disorders. The aim is to improve setting and pursuit of personal relevant goals. GiF follows a 24-individual-sessions treatment manual. GiF includes five treatment phases: 1) Preparation, 2) Goal-setting, 3) Goal-pursuit, and 4) Reflection and preparation of autonomous goal-pursuit. The interventions include generating positive goals, behavioral activation, training of anticipatory pleasure, challenging demotivating beliefs, training of problem-solving skills and social skills training.


Locations(1)

Psychotherapeutische Hoschschulambulanz Universität Hamburg

Hamburg, Germany

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NCT05252039


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