Fuchs' Endothelial Dystrophy Clinical Trials

12 recruiting

Frequently Asked Questions

Common questions about Fuchs' Endothelial Dystrophy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting
Not Applicable

The Belgian Endothelial Surgical Transplant of the Cornea

Pseudophakic Bullous KeratopathyFuchs' Endothelial DystrophyCorneal Edema+2 more
University Hospital, Antwerp220 enrolled11 locationsNCT05436665
Recruiting
Phase 1

PVEK Corneal Implant For Treatment of Corneal Edema

Pseudophakic Bullous KeratopathyFuchs' Endothelial DystrophyCorneal Edema+1 more
Precise Bio15 enrolled3 locationsNCT07325097
Recruiting
Phase 3

Descemet Endothelial Thickness Comparison Trial II

Fuchs' Endothelial DystrophyFuchs DystrophyFuchs
Stanford University60 enrolled7 locationsNCT05275972
Recruiting
Phase 1

Study to Assess Safety and Tolerability of Multiple Doses of EO2002

Endothelial DysfunctionPseudophakic Bullous KeratopathyFuchs' Endothelial Dystrophy+5 more
Asociación para Evitar la Ceguera en México12 enrolled1 locationNCT05636579
Recruiting

A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia

KeratoconusFuchs' Endothelial DystrophyEctasia+1 more
Massachusetts General Hospital168 enrolled1 locationNCT02118922
Recruiting
Phase 4

The OPTIMISE Study

Intraocular PressurePseudophakic Bullous KeratopathyFuchs' Endothelial Dystrophy
Maastricht University Medical Center342 enrolled8 locationsNCT05716945
Recruiting
Phase 1

Safety and Efficacy of Tissue Engineered Endothelial Keratoplasty

Fuchs' Endothelial DystrophyBullous KeratopathyMild to Moderate Corneal Endothelial Decompensation+1 more
Singapore Eye Research Institute30 enrolled1 locationNCT04319848
Recruiting

FECD-TRACE: Fuchs' Endothelial Corneal Dystrophy TRAjectory and Correlation With Genotype in the United Kingdom

Corneal DystrophyFuchs' Endothelial DystrophyFuchs Dystrophy+2 more
University College, London500 enrolled1 locationNCT06881771
Recruiting
Phase 3

The Effects of Ripasudil in Patients With FED Undergoing Femtosecond Laser Assisted Cataract Surgery

CataractFuchs' Endothelial Dystrophy
Singapore Eye Research Institute120 enrolled1 locationNCT06048380
Recruiting
Not Applicable

Plasma Rich in Growth Factors in Corneal Endothelial Transplantation

Fuchs' Endothelial DystrophyCorneal Edema
University of Miami100 enrolled2 locationsNCT06261346
Recruiting
Not Applicable

Endothelial Side Up Inverted Femtosecond Laser Assisted DSAEK

Pseudophakic Bullous KeratopathyFuchs' Endothelial Dystrophy
Dar El Oyoun Hospital15 enrolled1 locationNCT06652321
Recruiting
Phase 4

Glanatec(R) for Descemet Stripping in Fuch's Endothelial Dystrophy

Fuchs' Endothelial Dystrophy
Marian Macsai, MD30 enrolled1 locationNCT03249337