RecruitingNCT05277272

INTO-HLH: A Disease Registry for Patients With Hemophagocytic Lymphohistiocytosis (HLH)

INTO-HLH- Insight Into the Natural History and Treatment Outcomes of Hemophagocytic Lymphohistiocytosis (HLH): A Disease Registry for Patients With HLH

Sponsor

Children's Hospital Medical Center, Cincinnati

Enrollment

200 participants

Start Date

Dec 31, 2021

Study Type

OBSERVATIONAL

Conditions

Hemophagocytic Lymphohistiocytoses

Summary

The purpose of this observational study is to collect data on the natural history of disease of patients with Hemophagocytic Lymphohistiocytosis (HLH) including diagnosis, treatments, responses, and outcomes.

Eligibility

Inclusion Criteria2

Patients with clinically suspected or confirmed HLH, including those meeting the HLH-2004 diagnostic criteria (primary or secondary forms, including malignancy) and other forms of HLH (macrophage activation syndrome \[MAS\], cytokine release syndrome \[CRS\], etc.)
Signed and dated informed consent and assent (adolescents)