RecruitingNCT05898477

Describing Treatment Outcomes and Responses in Lymphoma-associated Hemophagocytic Lymphohistiocytosis


Sponsor

University of Alabama at Birmingham

Enrollment

2,000 participants

Start Date

May 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of the study is to describe Hemophagocytic lymphohistiocytosis (HLH) in patients with lymphoma to identify possible therapeutic strategies to improve overall survival of the patients with lymphoma associated hemophagocytic lymphohistiocytosis.


Eligibility

Plain Language Summary

Simplified for easier understanding

This study is collecting data on treatment outcomes for patients with lymphoma who develop a serious and potentially life-threatening condition called HLH (hemophagocytic lymphohistiocytosis) — a severe inflammatory response where the immune system attacks the body's own tissues. **You may be eligible if...** - You have lymphoma and have developed HLH, meeting at least 5 of 8 standard diagnostic criteria (HLH-2004) - Or you have very high levels of specific blood markers (sCD25 and ferritin) that indicate HLH **You may NOT be eligible if...** - Your HLH developed more than 1 month after your lymphoma diagnosis (for aggressive lymphoma types) - Your treatment and response records are incomplete Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

University of Alabama at Birmingham

Birmingham, Alabama, United States

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NCT05898477


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