RecruitingPhase 2NCT05288790

Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT

Sponsor

Vanderbilt University Medical Center

Enrollment

250 participants

Start Date

Sep 18, 2023

Study Type

INTERVENTIONAL

Conditions

Cardiovascular Diseases HIV Infections Dysbiosis Alcohol Drinking Microtia

Summary

Among people living with HIV, heavy drinking increases the risk of heart disease and death. Studies suggest that alcohol changes the number and kind of bacteria in your gut and these changes increase the risk of heart disease and death. This randomized controlled trial will determine whether a pill containing healthy gut bacteria can increase the number good bacteria in the gut, lower levels of inflammation, and lower the risk of heart disease and death.

Eligibility

Min Age: 18 YearsMax Age: 89 Years

Plain Language Summary

Simplified for easier understanding

This study investigates how substances produced by gut bacteria (microbiome metabolites) and alcohol use affect heart disease risk in people living with HIV. The goal is to find ways to reduce the risk of cardiovascular disease in this population. **You may be eligible if...** - You are living with HIV - You are fluent in English **You may NOT be eligible if...** - You are not fluent in English - You do not have HIV Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.