Cytokine Expression in Psoriasis Patients With and Without Joint Involvement
Cytokine Expression in Sera, ex Vivo Stimulated Peripheral Blood Mononuclear Cells Culture, and Skin in Psoriasis - Comparison of Patients With and Without Joint Involvement
Poitiers University Hospital
40 participants
Aug 17, 2022
INTERVENTIONAL
Conditions
Summary
The objective of the resarch is to study the cytokine profile of patients with psoriatic arthritis and psoriasis in order to better understand the pathophysiology of the disease and the contribution of cytokines to the presence or absence of joint involvement. This research will compare cytokines levels in sera, in PBMC culture after LPS or CD3/CD28 agonist antibodies, and in skin biopsy.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
Blood sample collection
Skin sample collection
Locations(1)
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NCT05307809