RecruitingNCT05318599

Deep Learning Diagnostic and Risk-stratification for IPF and COPD

Deep Learning Diagnostic and Risk-stratification for Idiopathic Pulmonary Fibrosis and Chronic Obstructive Pulmonary Disease in Digital Lung Auscultations


Sponsor

Pediatric Clinical Research Platform

Enrollment

160 participants

Start Date

Apr 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

Idiopathic pulmonary fibrosis (IPF), non-specific interstitial pneumonia (NSIP), and chronic obstructive pulmonary disease (COPD) are severe, progressive, irreversibly incapacitating pulmonary disorders with modest response to therapeutic interventions and poor prognosis. Prompt and accurate diagnosis is important to enable patients to receive appropriate care at the earliest possible stage to delay disease progression and prolong survival. Artificial intelligence (AI)-assisted digital lung auscultation could constitute an alternative to conventional subjective operator-related auscultation to accurately and earlier diagnose these diseases. Moreover, lung ultrasound (LUS), a relevant gold standard for lung pathology, could also benefit from automation by deep learning.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study uses artificial intelligence (deep learning) to analyze CT scan images to better diagnose and predict disease progression in patients with IPF (a scarring lung disease) and other interstitial lung diseases. **You may be eligible if...** - You have been diagnosed with IPF (idiopathic pulmonary fibrosis) or another interstitial lung disease - You are able to provide informed consent **You may NOT be eligible if...** - You are unable to give consent - Your imaging data is not available or of insufficient quality Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICELung auscultation

Digital lung auscultation with the Eko core digital stethoscope (Eko Devices, Inc., CA, USA).

DEVICELung ultrasound

Lung ultrasonography

OTHERQuality of Life's questionnaires

Impact of the diseases on subjects' health-related quality of life measured with standardized questionnaires (K-BILD, CAT)

DIAGNOSTIC_TESTPulmonary functional tests

Spirometry, body-plethysmographic parameters and lung diffusion capacity for carbon monoxide will be measured.


Locations(1)

Centre Hospitalier du Valais Romand

Sion, Valais, Switzerland

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NCT05318599


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